Cell Lines and Cell Cultures
Thermo Scientific™ Tango™ EDG3-bla U2OS Cells
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ ADRA2A-bla U2OS Cells
The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ GALR1-bla U2OS Cells
The Tango™ GALR1 -bla U2OS cells contain the human Galanin Receptor 1 (GALR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ TACR2-NFAT-bla CHO-K1 Cells
GeneBLAzer™ TACR2-NFAT-bla CHO-K1 cells contain the human Tachykinin receptor 2 (TACR2), (Accession No. NM_001057) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ RARβ-UAS-bla HEK 293T Cells
RAR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor beta (RAR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ RXRβ-UAS-bla HEK 293T Cells
RXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Retinoid X Receptor beta (RXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells
LXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ ESRE-bla HeLa Cell Line
Endoplasmic Reticulum (ER) stress is associated with a variety of pathophysiological conditions, such as neurodegenerative diseases, diabetes, tumor growth under hypoxic conditions, and ischemic heart disease.
Thermo Scientific™ LanthaScreen™ IkB alpha GripTite™ Cell Line
The LanthaScreen™ IkB alpha GripTite™ cell line contains a fusion protein consisting of the cDNA encoding for GFP and IkB (GFP is fused to the N-terminus of IkB alpha) under the control of a CMV promoter stably transfected into GripTite™ cells.
Thermo Scientific™ GeneBLAzer™ HCRTR1-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ HCRTR1-NFAT-bla CHO-K1 cells contain the human Hypocretin (Orexin) Receptor 1 (HCRTR1), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ ADORA1-bla U2OS Cells
The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ HTR7-CRE-bla CHO-K1 Cells
GeneBLAzer™ HTR7 CHO-K1 DA (Division Arrested) cells and HTR7-CRE-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 7 stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ ADRB2-CRE-bla CHO-K1 Cells
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ VPAC2-CRE-bla CHO-K1 Cells
GeneBLAzer™ VPAC2-CRE-bla CHO-K1 cells contain the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 2 (VPAC2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ NFAT-bla RA-1 Cell Line
B cell receptor (BCR)-mediated signaling pathways are important for B cell proliferation and differentiation. Abnormal B cell signaling has been linked to various diseases such as lupus, lymphoma, and various immune disorders.